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SOLVED:Enzymes that bind phosphoribosyl-5-phosphate (PRPP) have a common structural fold, the PRT fold, which unites them as a structural family. PRT here refers to the phosphoribosyl transferase activity displayed by some family members. Typically, in such reactions, PPi is displaced from PRPP by a nitrogen-containing nucleophile. Several such reactions occur in purine metabolism. Identify two such reactions where the enzyme involved is likely to be a PRT family member.
SOLVED:Enzymes that bind phosphoribosyl-5-phosphate (PRP…
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