San Francisco 49ers WR Brandon Aiyuk injury timetable feels like a completemystery and could have a huge impact on their ...

49ers star wide receiver Brandon Aiyuk is opening training camp on the active/physically unable to perform list and it ...

Even if Aiyuk was returning for the opener, the 49ers would likely use a pick on a receiver. Given that Aiyuk could miss half the year, picking that wide receiver earlier in hopes of finding a Day ...

San Francisco 49ers wide receiver Brandon Aiyuk is widely expected to start the 2025 season on the physically unable to perform (PUP) list, potentially sidelining him for at least the first four games ...

According to FTN Fantasy's adjusted games lost formula (which estimates the impact of injuries on teams), the Niners had a score of 166.6, which was the second-most of any team over the past two ...

Despite being a first-round pick, Arizona State receiver, Brandon Aiyuk wasn't expected to handle large duties for the San Francisco 49ers offense. On Monday, those expectations may have changed ...

Brandon Aiyuk injury updates. Jordan Schultz of Fox Sports reported Monday that tests confirmed Aiyuk had suffered a "season-ending knee injury" in Week 7 against Kansas City.

Brandon Aiyuk of the San Francisco reacts to an injury during an NFL football game against the Kansas City Chiefs at Levi’s Stadium on Oct. 20, 2024, in Santa Clara, Calif.

Before the injury, Aiyuk had two catches for 23 yards against the Chiefs in the 49ers' Week 7 game. He entered Week 7 with 23 catches for 351 yards and no touchdowns on the season.

That makes Brandon Aiyuk's season-ending knee injury an outright. At an up-and-down 3-4, the reigning NFC champion San Francisco 49ers can't be reliably counted on as a bona fide contender.

Aiyuk's injury marks another key offensive weapon missing for the 49ers. San Francisco star running back Christian McCaffrey still hasn't played in a game this season.