Brock Purdy returned from a six-game absence to throw three touchdowns as the 49ers (7-4) romped to a 41-22 win over the host ...

Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale ...

What's the Arizona Cardinals vs San Francisco 49ers score? Follow our live score updates for latest news, highlights, ...

The San Francisco 49ers had huge plays on both sides of the ball to earn a blowout win over the Arizona Cardinals. Here are ...

The Arizona Cardinals almost gave up as many points as Brissett had completions in this one though, as the San Francisco ...

Jacoby Brissett completed an NFL-record 47 passes, but San Francisco's offense rolled in Purdy's first game in weeks.

On the 49ers' first touchdown of the game, linebacker Akeem Davis-Gaither was matched up with star tight end George Kittle in ...

Oct 6, 2024; Santa Clara, California, USA; San Francisco 49ers tight end George Kittle (85) gestures after a catch against ...

SANTA CLARA, Calif. (AP) — Brock Purdy returned to the lineup and the San Francisco 49ers scored their most points in nearly ...

Nov 16, 2025; Glendale, Arizona, USA; San Francisco 49ers quarterback Brock Purdy (13) throws the ball while Arizona ...

The San Francisco 49ers had more players suffer injuries in Week 11 against the Arizona Cardinals. Here's what Kyle Shanahan ...

The San Francisco 49ers entered their second matchup against the Arizona Cardinals as favorites and won. Here were the worst ...