Nov 16, 2025; Glendale, Arizona, USA; San Francisco 49ers quarterback Brock Purdy (13) throws the ball while Arizona ...

San Francisco 49ers tight end George Kittle has been thoroughly impressed by what he's seen from defensive lineman Alfred ...

McCaffrey caught all five of his targets for 40 yards. He picked up three first downs and a touchdown, and also had a nice ...

The San Francisco 49ers are dealing with multiple new injuries after Sunday's win in Arizona, including one to their kicker.

The 49ers have their franchise quarterback back. "He was vintage Brock," Christian McCaffrey said. "That's a huge compliment.

A former NFL star accused the Arizona Cardinals of point-shaving against the 49ers on Sunday after San Francisco cruised to a ...

The San Francisco 49ers and Carolina Panthers are in a race for a playoff spot, but the 49ers are favored big in their Week ...

On a 70-yard, first-quarter drive that made the score 13-0, the 49ers needed only five plays to reach the end zone with three ...

The 49ers' team captains stepped up in Arizona. One of them, George Kittle, said the team is positioned right where it needs ...

Brock Purdy returned from a six-game absence to throw three touchdowns as the 49ers (7-4) romped to a 41-22 win over the host ...

For the first time since Week 1, the San Francisco 49ers had all of their starters back. Sure enough, it equates to their ...

The San Francisco 49ers entered Sunday in Week 11 with a healthy team, at least in terms of players on the roster.