Brock Purdy came through the Arizona game healthy, but kicker Eddy Piñeiro and linebacker Tatum Bethune did not.

San Francisco 49ers head coach Kyle Shanahan said he had big comebacks in mind when he kept Christian McCaffrey on the field ...

For the better part of his young, meteoric career, Brock Purdy has been shackled to that last, reductive label. He was ...

E ver since training camp last year, the San Francisco 49ers have been hit with one injury to a key player after another. They haven’t gotten any type of respite from the injury bug, and it resulted ...

It wouldn't be a normal victory Monday for the San Francisco 49ers without Kyle Shanahan providing discouraging injury news.

So much went right — and some went wrong — as the 49ers walloped the host Arizona Cardinals 41-22 in Brock Purdy’s comeback.

The San Francisco 49ers won't get star WR Brandon Aiyuk back in time for their Week 12 matchup against the Carolina Panthers.

Albert Breer and Kyle Brandt argue that San Francisco 49ers coach Kyle Shanahan deserves consideration for the 2025 NFL Coach ...

The San Francisco 49ers kicking woes aren't over just yet.

San Francisco 49ers head coach Kyle Shanahan provided an unfortunate injury return timeline update for Brandon Aiyuk.

See where every NFL backup quarterback stands in 2025, from reliable backups to weakest QB rooms in the league.

Linebacker Tatum Bethune and kicker Eddy Piñeiro will be out indefinitely after sustaining injuries in the 49ers’ 41-22 ...