Justin Timberlake fans are feeling downright disappointed in a star they feel they've come to know over his many years in the spotlight.

Justin Timberlake opens up about his health, revealing a 'relentlessly debilitating' Lyme disease diagnosis as he bids farewell to his world tour.

FRIDAY, Aug. 1, 2025 (HealthDay News) — Singer Justin Timberlake has Lyme disease, a condition he says caused nerve pain, fatigue and other symptoms during his recent tour. In a post on Instagram Thursday, the 44-year-old pop star said the tick-borne illness left him feeling “relentlessly debilitated, both mentally and physically.”