Arizona Cardinals quarterback Jacoby Brissett had an eye-popping statline on Sunday in the team's 41-22 loss to the San ...

Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale ...

In the Arizona Cardinals ' 41-22 loss to the San Francisco 49ers on Sunday, 20 players participated in at least one of the 79 ...

Brock Purdy returned from a six-game absence to throw three touchdowns as the 49ers (7-4) romped to a 41-22 win over the host ...

The Arizona Cardinals are searching for answers after a second straight embarrassing loss to an NFC West rival.

Arizona Cardinals quarterback Jacoby Brissett completed an NFL record 47 passes on Sunday, breaking the previous single-game ...

The 49ers' team captains stepped up in Arizona. One of them, George Kittle, said the team is positioned right where it needs ...

San Francisco 49ers tight end George Kittle (85) celebrates his touchdown catch with teammates Jake Tonges (88) and Kendrick ...

Much happened in between, including Buffalo Bills QB Josh Allen accounting for six touchdowns, Arizona Cardinals QB Jacoby Brissett breaking the NFL record with 47 completed passes and the debut of ...

Former Pro Bowl RB LeSean McCoy believes the Arizona Cardinals point shaved in their Week 11 loss to the San Francisco 49ers.

When Kyler Murray went down with a foot injury, no one could have predicted Jacoby Brissett would fill in just as well, or ...

Joe Serpico shares his top fantasy football waiver-wire pickups heading into Week 12, including Cardinals QB Jacoby Brissett.