ARIZONA -- Arizona Cardinals TE Trey McBride was flagged for an unsportsmanlike conduct penalty in their Week 11 loss to the San Francisco 49ers, a penalty that drew plenty of criticism online and around the football world. The flag came after McBride celebrated a first down.

Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale.

After another inept defensive performance and a hallow offensive output, the Arizona Cardinals sit at 3-7 and now host the Jacksonville Jaguars on Sunday. The Jaguars only open as small favorites, so things are not completely off the rails yet.

Arizona Cardinals head coach Jonathan Gannon says talk of him being on the 'hot seat' as far as his job comes with being an NFL head coach.

Former Pro Bowl RB LeSean McCoy believes the Arizona Cardinals point shaved in their Week 11 loss to the San Francisco 49ers.

Oct 6, 2024; Santa Clara, California, USA; San Francisco 49ers tight end George Kittle (85) gestures after a catch against the Arizona Cardinals during the fourth quarter at Levi's Stadium. Mandatory Credit: Darren Yamashita-Imagn Images / Darren Yamashita-Imagn Images

The rookie fourth-rounder was busy in the second start of his NFL career, leading the Cardinals with 12 stops. With Mack Wilson (ribs) placed on injured reserve prior to Sunday's contest, Simon should serve as the Cardinals' starting middle linebacker for at least the next three games and for as long as the former is on IR.

Bam Knight is active for the Arizona Cardinals' Week 11 game against the San Francisco 49ers and will likely lead the backfield, as he has recently.

ARIZONA -- The Arizona Cardinals are no strangers to adjusting to opposing fans at State Farm Stadium, though the San Francisco 49ers tend to travel among the best in the NFL in terms of away support.