Google’s Gemma-based C2S-Scale model helped Yale find a drug combo that boosts tumor antigen presentation, pointing to a new ...
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Endocrine Therapy Resistance in HR+/HER2- Breast Cancer: A Common Clinical Challenge
Endocrine therapy typically slows cell cycle progression by reducing cyclin D1, which partners with CDK4/6 to promote cell ...
Researchers identify FGFR4, FLT1, and WNT5A as key biomarkers and suggest dovitinib and nintedanib as new targeted therapies ...
Scientists have developed compounds that selectively block a crucial interaction between RAS and the enzyme PI3K, a driver of tumor growth. Scientists from the Francis Crick Institute and Vividion The ...
The model identified silmitasertib (CX-4945), a kinase CK2 inhibitor, as a potential treatment that could enhance antigen ...
Glioblastoma (GBM), a malignant tumor originating from glial, is the most common primary tumor of the central nervous system and the most aggressive form of glioma. Despite surgery, radiation, and ...
This foundation model has not only decoded cellular language but has also generated and experimentally validated a new ...
Reactive Oxygen Species (ROS) play a multifaceted role in the biology of cancer, acting as a double-edged sword. These highly ...
Chronic stress fuels cancer by releasing stress mediators that remodel the tumor and stromal cells, promoting immune evasion, angiogenesis, and metastasis. A review in Science Bulletin underscores how ...
Scientists have found a way to transform hard-to-treat tumors into targets for the immune system. Using two protein ...
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