Original research: Mortality associated with moderate and severe mitral regurgitation in 608 570 men and women undergoing ...

Background Effective management of coexisting heart failure (HF), chronic kidney disease (CKD) and type 2 diabetes mellitus ...

Following injury, many organs are capable of rapid regeneration of necrotic tissue to regain normal function. In contrast, ...

For over two decades, a ‘treatment-risk paradox’ has been described in older adults with cardiovascular disease, with ...

Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide. Macrophages are important components of the internal immune cells, which profoundly affects the internal ...

Background There is substantial interest in the cardiovascular effects of e-cigarette use, highlighting the need to update our knowledge on the subject. We conducted this review to analyse whether ...

Objective To investigate sex differences in prevalence, treatment and control of major cardiovascular risk factors in England. Methods Data from the Health Survey for England 2012–2017 on ...

Missed opportunities to manage complex comorbidity of heart failure, type 2 diabetes mellitus and chronic kidney disease: a retrospective cohort study ...

Background Pulmonary hypertension (PHT) lacks community prevalence and outcome data. Objective To characterise minimum ‘indicative’ prevalences and mortality data for all forms of PHT in a selected ...

Background Menopause is a timely opportunity to screen for cardiovascular disease (CVD) and intervene with healthier lifestyles. We investigated the association between premature/early menopause and ...

Objective To assess the long-term functional and health-related quality-of-life (HRQoL) outcomes for out-of-hospital cardiac arrest (OHCA) survivors stratified by initial defibrillation provider.