The benefits of dietary fiber extend beyond digestive health, as dietary fiber-derived metabolites produced by gut microbiota ...

The study, published in the journal iScience, found that creatine helps activate a group of immune cells that decide whether the body attacks a tumor at all. The same laboratory h ...

Dendritic cells (DCs) are a heterogeneous group of antigen-presenting innate immune cells that regulate adaptive immunity, including against cancer. Therefore, understanding the precise activities of ...

Butyrate, produced when gut bacteria ferment dietary fiber, was shown to influence immune-cell identity, trafficking, and ...

Creatine, the organic acid that is popularly taken as a supplement by athletes and bodybuilders, supercharges a critical class of immune cells that activate and prepare the body’s key cancer-fighters, ...

The immune system must be able to quickly attack invaders like viruses, while also ignoring harmless stimuli, or allergies can result. Immune cells are known to ignore or "tolerate" molecules found in ...

Farnesyl pyrophosphate (FPP), an intermediate of cholesterol biosynthesis in the mevalonate pathway, prolongs the survival of migratory dendritic cells (mig-DCs) by remodelling mitochondrial structure ...

The immune system consists of inflammatory and regulatory T cells (Tregs) that promote or dampen immune activity, respectively. These cells react to specific antigens that specialized cells like ...

A type 1 conventional dendritic cell (cDC1), magnified 100 times, that has been supercharged with chimeric antigen receptors to better find and prime anti-tumour immune responses. The project, led by ...

Indiana University School of Medicine researchers have made significant progress in understanding how cells communicate during inflammation. The study, recently published in PNAS, was conducted over a ...

Cancer immunotherapy transforms a patient’s immune cells into a “search‑and‑destroy” force against tumors. But many cancers learn to camouflage themselves from dendritic cells—the immune system’s ...

The immune system must be able to quickly attack invaders like viruses, while also ignoring harmless stimuli, or allergies can result. Immune cells are known to ignore or “tolerate” molecules found on ...