Animals use small RNA pathways, such as PIWI-interacting RNA (piRNA) and small interfering RNA (siRNA), to silence harmful genetic elements. In Caenorhabditis elegans, piRNA pathway components are ...

WEST LAFAYETTE, Ind. — Like tiny superheroes, small, naturally occurring segments of RNA can block multiple molecular paths that cancer cells use to grow and spread, a substantial advantage over even ...

RNA-based therapeutics have made substantial clinical advances, primarily due to the unique chemical and biological profiles of RNA molecules. As evidenced by the approval of various RNA drugs, some ...

A team led by UNC School of Medicine researchers is the first to confirm that a small molecule called miR-29 plays a role in driving aging. Their new findings are published in Communications Biology.

Genetic editing holds promise to treat incurable diseases, but the most popular method—CRISPR—sometimes does more harm than good. A new study from University of California San Diego and Yale ...

Viruses need hosts. Whether it's measles, the flu or coronavirus, viral pathogens cannot multiply or infect other organisms without the assistance of their hosts' cellular infrastructure. However, ...

A team of researchers led by University of California, Riverside biomedical scientists has identified a small, previously overlooked small RNA molecule that plays a major role in controlling the ...

Genes are not passed on exclusively from parents to their offspring. Some are mobile and can also jump to other species, as ...

Not everything inside us is, strictly speaking, us. The closer we look at the genome, the more we appreciate the role of small RNAs in what we call epigenetic inheritance. That’s when traits get ...

The discovery of siRNA and its role in RNAi was a groundbreaking finding in the field of molecular biology. In 1998, Andrew Fire and Craig Mello published a seminal paper describing the phenomenon of ...

Small RNA therapeutics can modulate multiple genes. This ability may counter tumor adaptation and resistance, overcoming the ...

In this interview, industry expert Dr. Lohit Khera discusses the evolving role of microRNA in research, diagnostics, and precision medicine. He also highlights the latest RNA extraction and analysis ...