Scientists have developed compounds that selectively block a crucial interaction between RAS and the enzyme PI3K, a driver of tumor growth. Scientists from the Francis Crick Institute and Vividion The ...

Chronic stress fuels cancer by releasing stress mediators that remodel the tumor and stromal cells, promoting immune evasion, angiogenesis, and metastasis. A review in Science Bulletin underscores how ...

Panel A summarizes the conventional model of how oncogenic RAS guanosine triphosphatases (i.e., Kirsten rat sarcoma viral oncogene homologue [KRAS], neuroblastoma RAS viral oncogene homologue [NRAS], ...

Google’s Gemma-based C2S-Scale model helped Yale find a drug combo that boosts tumor antigen presentation, pointing to a new ...

P-cadherin is a protein commonly found on malignant cancer cells and has been used as a target for antibody-based cancer treatments. UC Davis biomedical engineers have discovered that when an antibody ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

This review systematically examines the potential of spices and culinary herbs (e.g., turmeric, garlic, ginger) for breast cancer (BC) prevention and treatment, elucidating their underlying mechanisms ...

Tumors are not a comfortable place to live: oxygen deficiency, nutrient scarcity, and the accumulation of sometimes harmful ...