As the San Francisco 49ers take on the Chicago Bears in Sunday's clash of two top teams in the NFC, the former has been without a key player in linebacker Fred Warner, suffering from a significant ankle injury. With the talk of Warner returning to the 49ers in the playoffs, the latest reporting gives more insight into that being a possibility.

The 49ers have a strong chance to make the playoffs despite having the toughest remaining schedule. Here's what you need to know.

The San Francisco 49ers get a much-needed week off before starting a tough stretch to finish off their 2025 regular season schedule.

Get the full 49ers practice and media schedule ahead of the Week 16 matchup vs. the Colts, including press conferences with Kyle Shanahan and Brock Purdy.

Indianapolis Colts host the San Francisco 49ers for NFL Monday Night Football tonight in Week 16. MNF time, TV schedule, how to watch live and streaming.

The San Francisco 49ers have beaten the Indianapolis Colts 48-27 on “Monday Night Football” behind Brock Purdy ’s career-high five touchdown passes. Christian McCaffrey racked up 146 total scrimmage yards and caught two touchdowns, while George Kittle totaled seven receptions for 115 yards and a TD before leaving the game with an ankle injury.

The SportsLine Projection Model has revealed its Chicago vs. San Francisco picks for 'Sunday Night Football' in Week 17

The Indianapolis Colts host the San Francisco 49ers in NFL Week 16 action on 'Monday Night Football': Live score updates, highlights, where to watch.