Dendritic cells occupy a pivotal role at the nexus of metabolism and immune regulation, employing distinct bioenergetic programmes to calibrate antigen uptake, processing and presentation. In their ...

The benefits of dietary fiber extend beyond digestive health, as dietary fiber-derived metabolites produced by gut microbiota ...

Dendritic cells (DCs) in teleost fish are pivotal antigen-presenting cells that bridge the innate and adaptive arms of immunity. Morphologically and functionally analogous to their mammalian ...

Butyrate, produced when gut bacteria ferment dietary fiber, was shown to influence immune-cell identity, trafficking, and ...

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer—and how restoring their ...

The immune system consists of inflammatory and regulatory T cells (Tregs) that promote or dampen immune activity, respectively. These cells react to specific antigens that specialized cells like ...

A study led by researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has identified a mitochondrial "checkpoint" that enables dendritic cells to efficiently activate T ...

Chronic diabetic ulcers represent one of the most challenging complications in modern healthcare, affecting over 131 million people worldwide and generating approximately $755 billion in annual ...