The endoplasmic reticulum (ER) is central to protein synthesis, folding and modification, ensuring that the proteome of a cell remains functional and balanced. When the ER is overwhelmed by an ...

Janelia researchers have uncovered a novel way that two of the structures inside cells-the endoplasmic reticulum (ER) and lysosomes-coordinate the production of proteins, highlighting how interactions ...

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...

Researchers reveal how cells regenerate protein factories at endoplasmic reticulum. Researchers at LMU and Stanford University reveal how cells regenerate protein factories at endoplasmic reticulum.

The endoplasmic reticulum is usually the biggest organelle in eukaryotic cells and is invovled in many crucial processes... | Cell And Molecular Biology ...

Supersulfides play a fundamental role in longevity: maintaining protein folding in the endoplasmic reticulum (ER) and energy production in mitochondria. Ikoma, Japan – Supersulfides are gaining ...

A cell contains many specialized subunits, called organelles, that carry out important tasks such as energy generation, protein synthesis, and calcium outflux. But what happens when something goes ...

Tsukuba, Japan—Researchers have been studying the transcription factor SREBP, a critical regulator of lipid biosynthesis. Precursor SREBP proteins, located in the endoplasmic reticulum (ER) of the ...