A study published in Science reveals a cellular mechanism involved in the inheritance of genetic mutations. The study also ...

Accumulation of damaged mitochondria in neurons is a hallmark of neurodegenerative disorders including Alzheimer disease (AD). A new study in Nature Neuroscience reports impaired mitophagy — the ...

Mission Therapeutics raises $13.3M to advance its USP30 inhibitor MTX325 into Phase I trials for Parkinson’s, targeting ...

A team of cell biologists from the Max Perutz Labs at the University of Vienna has identified a previously unrecognised pathway that activates mitophagy, a process in which damaged mitochondria are ...

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest ...

Autophagy is a natural, conserved process where cells degrade and recycle their own components, including damaged proteins and organelles. This targeted removal is orchestrated by cargo receptors, ...

Scientists discovered a key molecular switch to keep neurons healthy by controlling the disassembly and assembly of their ...

Mitophagy is a selective form of autophagy via which the damaged mitochondria are cleared via the autophagy-lysosome pathway. Mitophagy is an essential part of mitochondrial quality control and plays ...

Despite the promise of new medications that promote cancer cell death in people with acute myeloid leukemia, leukemic cells often adopt features that let them evade the drugs' effects within a year.