Scientists uncover a new “recipe” that shows how exhausted T cells can be reprogrammed to regain their ability to attack tumors.

A multi-institutional study led by researchers at UNC Lineberger Comprehensive Cancer Center, the Salk Institute for Biological Studies, and UC San Diego has uncovered new genetic rules that determine ...

For San Diego researchers and the wider immunotherapy community, the atlas functions as a practical roadmap. It does not ...

A new predictive framework reprograms T cells to sustain immune memory while preserving their ability to fight cancer and infections.

Scientists discovered key genetic factors that determine whether a T cell acts as a powerful disease fighter or enters an ...

Cancer immunotherapy has been transformed by engineered T cells, but those bespoke treatments are slow, expensive, and out of reach for many patients who need help quickly. A new way to generate vast ...

Researchers from MIT and Harvard University have discovered a new way to create effective cancer-fighting cells, a new study revealed. The peer-reviewed study detailed research that was conducted in ...

New research shows lymph nodes aren’t just cancer bystanders, they’re the command centers fueling immune attacks. Surgically removing them along with tumors may weaken treatment, while preserving them ...

Killer immune cells destroy cancer cells and cells infected by virus. These CD8 + T cells are activated after detection of viral infection or growth of “non-self” tumor cells. However, in chronic ...

Supercharged ‘natural killer’ cells could become a potent way to reset a disordered immune system — and thus quench some autoimmune disorders. Results from two small clinical trials suggest that ...