The immune system’s capacity to distinguish self from non-self is in large part mediated by immunoglobulins, with IgG playing a pivotal role in both protective and pathological responses.

Proceedings of the National Academy of Sciences of the United States of America, Vol. 76, No. 8 (Aug., 1979), pp. 4071-4074 (4 pages) An electron-density map of the mouse galactan-binding ...

Vertebrates with a defined immune system, such as humans, have an immune response consisting of an innate and adaptive response, also known as a specific response. The specific response is tailored to ...

This is a preview. Log in through your library . Abstract Pathogenic bacteria have developed complex and diverse virulence mechanisms that weaken or disable the host immune defense system. IdeS ...

Fc receptors (FcRs) are a group of glycoproteins that belong to the immunoglobulin superfamily and are classified, like Fc alpha receptors (FcαRs), Fc gamma receptors (FcγRs) and Fc epsilon receptors ...

IdeS IgG protease shows promise for Myasthenia Gravis, Immune Thrombocytopenia, and dozens of other IgG-driven autoimmune diseases. The wild type enzyme elicits potent anti-drug antibodies (ADA) that ...