Researchers with McMaster University have discovered that the protein mutated in patients with Huntington's Disease doesn't repair DNA as intended, impacting the ability of brain cells to heal ...
Researchers with McMaster University have discovered that the protein mutated in patients with Huntington disease doesn't repair DNA as intended, impacting the ability of brain cells to heal ...
A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease ...
Huntington's disease is a neurodegenerative disorder that is usually fatal about 15 to 20 years after a patient is diagnosed. It is known to be caused by an aberrant repetitive sequence (CAG) in the ...
Mayo Clinic researchers say they and their colleagues have made a discovery that sheds light into the development of Huntington’s disease. The researchers, collaborating with others from the National ...
A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington’s disease ...
Inherited repeat mutations in the HTT gene expand in neurons over decades before crossing a toxic threshold, revealing a long time window for therapy. CAG repeats in HTT are unstable, meaning that the ...
The sequence pattern matters: Interruptions or “hitches” and loss of these within the C-A-G repeat and C-C-G repeat stretches play a major role as to when symptoms start with loss of interruptions ...
People genetically susceptible to Huntington's disease often see their movement, mood, and cognition decline slowly over time. The cause is related to expansion of repeating DNA units, in which ...
Researchers have made an important Huntington's disease discovery. They have found that the protein mutated in patients with Huntington's disease doesn't repair DNA as intended, impacting the ability ...
A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease ...
Researchers with McMaster University have discovered that the protein mutated in patients with Huntington’s Disease doesn't repair DNA as intended, impacting the ability of brain cells to heal ...
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