Scientists have long been puzzled by how maturing red blood cells manage to produce all the hemoglobin they need to carry ...

Hemoglobin disorders such as HbS and HbC affect millions of people worldwide. Countries around the world spend substantial resources each year identifying carriers, often relying on detailed ...

On Friday, the U.S. Food and Drug Administration (FDA) approved a pair of gene therapies for the painful and potentially fatal blood disorder, sickle cell disease (SCD)–including the first-ever CRISPR ...

Scientists have long been puzzled by how maturing red blood cells manage to produce all the hemoglobin they need to carry oxygen to tissues, even ...

Stuart Orkin, the Harvard Medical School David G. Nathan Distinguished Professor of Pediatrics at Dana-Farber Cancer ...

Hemoglobin, long celebrated for ferrying oxygen in red blood cells, has now been revealed to play an overlooked—and potentially game-changing—antioxidant role in the brain. "The key was to uncover ...

The United States Food and Drug Administration has announced its approval of the first genetic therapy treatment for sickle cell disease. The drug exagamglogene autotemcel, commercially know as ...

Sickle cell disease (SCD) is a group of hereditary red blood cell disorders. Sickle cell anemia is a type of SCD that occurs when a person inherits genes containing an atypical form of hemoglobin.

AstraZeneca Plc (NASDAQ:AZN) released data from the Phase 3 ALPHA trial of danicopan as an add-on to the standard of care for paroxysmal nocturnal hemoglobinuria (PNH). The data showed that danicopan ...

In neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Parkinson’s, and Alzheimer’s, healthy brain cells are damaged by aberrant reactive oxygen species (ROS). A potential ...