Lonza has announced that it now provides an expansive selection of high-resolution Human Leukocyte Antigen (HLA)-typed primary cells spanning all major cell and tissue types. The ready-typed lots will ...

Somatic mutations in HLA genes were detected in the tumor data of five patients, and somatic HLA gene loss of heterozygosity was identified in the tumor data of five patients. Complete or partial ...

Determining the specificity of HLA antibodies is arguably one of the most important contributions by the HLA laboratory today. For patients that have low-to-moderate levels of antibody, using a ...

“Since the discovery of transplantation as a life-saving therapy for blood malignancies by Dr. E Donnall Thomas, there have been major advances that have significantly lowered the side effects and ...

A subset of neutrophils as a predictive biomarker for immunotherapy response in patients with non–small-cell lung cancer and melanoma. This is an ASCO Meeting Abstract from the 2023 ASCO Annual ...

HLAs sit on the surface of cells and have enormous variability from person to person, serving somewhat as molecular fingerprints. When the body encounters unfamiliar versions of these proteins from a ...

The human leukocyte antigen (HLA) molecules are proteins expressed on the cell membrane that can activate circulating immune cells, T cells specifically, for targeted cell killing. Alternatively, ...

The CiRA Foundation has published a paper in Med that provides an update on the iPS Cell Stock Project. The reprogramming of peripheral or cord blood from 7 donors who are homozygous for HLA-A, -B, ...

When a patient undergoes an organ transplant, failure to match the donor and recipient can lead to the recipient's immune system attacking the new organ, a process triggered by a specific HLA (human ...

The Transplant Company™, a leading precision medicine company focused on the discovery, development, and commercialization of clinically differentiated, high‑value healthcare solutions for transplant ...