Podocytes are highly specialised epithelial cells that enwrap glomerular capillaries, forming the final layer of the filtration barrier in the kidney. Their elaborate foot processes interdigitate and ...

The glomerular filtration barrier is a highly specialised tri-layer structure within the renal corpuscle, which allows selective passage of water and small solutes while retaining larger proteins and ...

A team of scientists now reports an approach that enables the differentiation of human induced pluripotent stem (iPS) cells into mature podocytes with more than 90 percent efficiency. Linking the ...

The inherited forms of proteinuria comprise a heterogeneous group of rare renal diseases in which glomerular dysfunction and proteinuria are prominent. Despite the rarity of hereditary proteinuria ...

Proteinuria is a defining feature of focal segmental glomerulosclerosis, typically accompanied by hypoalbuminemia, hypercholesterolemia, and peripheral edema. The nephrotic syndrome in children is ...

Adopting a kidney-friendly diet like the DASH or Mediterranean diet and managing sodium, potassium, phosphorus, and protein intake may help improve GFR by reducing kidney strain. Maintaining heart ...

Glomeruli are at the heart of renal function, and yet are only part of an intact nephron. They are of irreplaceable value in maintaining homeostasis. The intact nephron theory: Each nephron is a ...

What Is a Creatinine Test? A creatinine test, also called a serum creatinine test, measures how well your kidneys are working. Creatinine is a waste product from the normal breakdown of muscle tissue.