The San Francisco 49ers still have a chance to claim the one seed in the NFC playoff bracket with a win in Week 16 over the ...

The Buffalo Bills are on the verge of the postseason. It'll only take one little nudge to secure a clinch for the Bills, who are 11-4 after their win Sunday over the Cleveland Browns. It was a bit of ...

The San Francisco 49ers and Buffalo Bills have a lot of similarities this season. Both are top playoff contenders, but have a team in their division that's likely to run away with the division title.

There's a reason the 49ers are the favorites against the Buffalo Bills. That's right. Oddsmakers have given the 49ers, who are 5-6, a one-point advantage over the Buffalo Bills. who are 8-3. And not ...

This week's edition of the regularly-scheduled "Monday Night Football" game sees the first-place Buffalo Bills head to Arizona to take on the San Francisco 49ers. The Bills enter this contest at 8-3, ...

In a disappointing season, a team typically reaches a point of no return, a realization that, “We have met the enemy, and it is us.” A late collapse against Seattle, a 38-10 drubbing in Green Bay, a ...

How did we get to the NFL Christmas Day slate and just two weeks remaining in the regular season already? This year has ...

Week 10 of the regular season brought the 2025 NFL playoff picture more into focus with some contenders trying to create separation with big performances and some changing of the guard in the muddled ...

Josh Allen accounted for four total touchdowns, though two of them came on the same play, as the Bills won their seventh straight game and clinched their fifth straight division title. Allen threw for ...

Blazin’ 5 for Week 11: Bills, Seahawks & 49ers highlight Colin’s best bets | The Herd Colin Cowherd lists his best bets entering Week 11, including the Buffalo Bills over the Tampa Bay Buccaneers, the ...