Angiotensin-converting enzyme (ACE) expression by myeloid cells is increased in response to infection. Forced ACE overexpression in mouse macrophages increases their ability to respond to infection ...

Hypertension is a major risk factor of various diseases including stroke, heart failure, vascular disease, and kidney disease. Angiotensin II, which is produced by the renin-angiotensin system, ...

Losartan may help stop the epileptic process in certain patients with hypertension. An observational study that analyzed medical records of 2.26 million patients with hypertension found a roughly 30% ...

Role of the RAAS in the Pathophysiology of Heart Failure ACE inhibitors have no effect on angiotensin II formed by alternate pathways. In contrast, ARBs would be expected to inhibit the biologic ...

Atrial fibrillation, or AFib, is the most common heart rhythm disorder. With AFib, the beating of the upper chambers of your heart (the atria) becomes irregular, and blood has a harder time reaching ...

Cardiovascular illnesses, such as high blood pressure and heart problems, are often treated with angiotensin-converting enzyme (ACE) inhibitors. The ACE inhibitors lower blood pressure by relaxing ...

Angiotensin converting enzyme inhibitors are a class of oral medications that act primarily through blockade of the angiotensin converting enzyme. This enzyme converts angiotensin I to angiotensin II.

A phase 1 multiple-ascending dose study to evaluate the safety and tolerability of XmAb23104 (PD-1 x ICOS) in subjects with selected advanced solid tumors (DUET-3). This is an ASCO Meeting Abstract ...

Patients who start their blood pressure treatment with angiotensin receptor blocker (ARB) drugs continue with the same medicine to a greater extent than patients who start out with other drugs.