ROS-mediated PKCζ S-glutathionylation at Cys48 is essential for LKB1 cytoplasmic localization and AMPK activation upon energy stress. AMP-activated protein kinase (AMPK) plays a central role in ...
Dr. Tao Ma and colleagues synthesize emerging evidence on AMPKα isoforms, proposing isoform-specific targeting as a novel therapeutic strategy for Alzheimer's disease and related dementias ...
Melkani’s lab study, titled "Time-restricted feeding promotes muscle function through purine cycle and AMPK signaling in Drosophila obesity models,” was recently published in Nature Communications.