ARIZONA -- Arizona Cardinals TE Trey McBride was flagged for an unsportsmanlike conduct penalty in their Week 11 loss to the San Francisco 49ers, a penalty that drew plenty of criticism online and around the football world. The flag came after McBride celebrated a first down.

After another inept defensive performance and a hallow offensive output, the Arizona Cardinals sit at 3-7 and now host the Jacksonville Jaguars on Sunday. The Jaguars only open as small favorites, so things are not completely off the rails yet.

Arizona Cardinals head coach Jonathan Gannon says talk of him being on the 'hot seat' as far as his job comes with being an NFL head coach.

The rookie fourth-rounder was busy in the second start of his NFL career, leading the Cardinals with 12 stops. With Mack Wilson (ribs) placed on injured reserve prior to Sunday's contest, Simon should serve as the Cardinals' starting middle linebacker for at least the next three games and for as long as the former is on IR.

The Arizona Cardinals are searching for answers after a second straight embarrassing loss to an NFC West rival.

Sunday will be the 2025 debut for Arizona Cardinals outside linebacker BJ Ojulari. Among the roster moves the Cardinals made on Saturday ahead of their Sunday game in Week 11 against the San Francisco 49ers, Ojulari was activated from the PUP (physically unable to perform) reserve.

ARIZONA -- The Arizona Cardinals are no strangers to adjusting to opposing fans at State Farm Stadium, though the San Francisco 49ers tend to travel among the best in the NFL in terms of away support.

NFL Week 12 odds, picks, predictions, TV channel, streaming information for Sunday football game between Jacksonville Jaguars and Arizona Cardinals.