The St. Louis Cardinals need some more starting pitching this offseason with the rotation completely up in the air for the 2026 season. Luckily, the organizati

Expert recap and game analysis of the San Francisco 49ers vs. Arizona Cardinals NFL game from November 16, 2025 on ESPN.

The Arizona Cardinals entered their game on Sunday against the San Francisco 49ers with a long list of injuries. After their 41-22 loss, they left with even more. However, there isn't much to know yet. But three Cardinals players exited the game and did not return.

The St. Louis Cardinals will be making a lot of trades this winter as they prepare to rebuild for 2026. They need to offload contracts but also find ways to add

The Arizona Cardinals are searching for answers after a second straight embarrassing loss to an NFC West rival.

On a 70-yard, first-quarter drive that made the score 13-0, the 49ers needed only five plays to reach the end zone with three plays gaining 13 and 25 by Demarcus Robinsion and Jauan Jennings, respectively, and a 30-yard touchdown by Kittle.

The 49ers' team captains stepped up in Arizona. One of them, George Kittle, said the team is positioned right where it needs to be.

ARIZONA -- Arizona Cardinals TE Trey McBride was flagged for an unsportsmanlike conduct penalty in their Week 11 loss to the San Francisco 49ers, a penalty that drew plenty of criticism online and around the football world. The flag came after McBride celebrated a first down.