San Francisco 49ers head coach Kyle Shanahan provided an unfortunate injury return timeline update for Brandon Aiyuk.

Kyle Shanahan said Brock Purdy "checked out all right" after his first game back. Linebacker Tatum Bethune, however, didn't fare as well.

SANTA CLARA, Calif. (AP) — Brock Purdy returned to the lineup and the San Francisco 49ers scored their most points in nearly two years. While Purdy looked sharp in the 41-22 victory over the Arizona Cardinals on Sunday, the reasons behind the big scoring output have to do with a lot more than just the change at quarterback.

The 49ers drafted Martin to play their WILL spot, which is the weakside linebacker spot. This is the position Dee Winters plays, not Warner and Bethune. Warner played the MIKE, which is in the middle, and gets the defense aligned. The WILL is more about run-and-chase. They are asked to do different things.

A former NFL star accused the Arizona Cardinals of point-shaving against the 49ers on Sunday after San Francisco cruised to a 41-22 victory in the NFC West showdown.

Wide receiver Brandon Aiyuk will go at least another week without practicing, 49ers coach Kyle Shanahan said on Monday. Aiyuk is “week to week,” Shanahan said. He remains on the physically unable to perform list as he looks to round back into playing condition after sustaining a severe right knee injury last season.

Brock Purdy came through the Arizona game healthy, but kicker Eddy Piñeiro and linebacker Tatum Bethune did not.

NBC Sports Bay Area asked the 49ers Faithful how many games San Francisco will win to close out the 2025 NFL regular season.

Head coach Kyle Shanahan of the San Francisco 49ers looks on during warmups before the game against the Arizona Cardinals at State Farm Stadium on Nov. 16, 2025 in Glendale, Ariz. A costly penalty by a San Francisco 49ers defensive player led head coach Kyle Shanahan to bench him and confront him on the sidelines.

The San Francisco 49ers kicking woes aren't over just yet.